- Evaxion created a genetic adjuvant technologies that boosts the immune responses of viral, bacterial and cancer vaccines
- Preclinically validated for each DNA and mRNA vaccines, and prepared for clinical testing
- Anticipated significant industry possible for DNA and mRNA vaccines against cancer, viral and bacterial ailments
COPENHAGEN, Denmark, May well 25, 2023 (GLOBE NEWSWIRE) — Evaxion Biotech A/S (NASDAQ: EVAX) (“Evaxion” or the “Company”), a clinical-stage biotechnology enterprise specializing in the discovery and improvement of AI-powered immunotherapies, nowadays unveils the technologies behind its novel, proprietary genetic adjuvant created to boost the effectiveness of DNA and mRNA vaccines for infectious ailments and cancer.
Newest information from the adjuvant system had been presented at Evaxion’s reside stream R&D Day, May well 25, 2023.
“We are excited to present this novel genetic adjuvant technologies to the worldwide scientific neighborhood. It boosts Evaxion´s personal DNA technologies and has the possible to strengthen the impact of practically any vaccine. We foresee a excellent industry possible in that this technologies seems to be hugely helpful in each DNA and mRNA primarily based vaccines against cancer as effectively as infectious ailments,” stated Per Norlén, CEO at Evaxion.
Evaxion´s novel genetic adjuvant carries the code for CCL19, a molecule identified to attract immune cells, notably antigen presenting cells, and can be encoded into either DNA or mRNA vaccines with the aim of boosting the immune response.
Newest information show that the genetic adjuvant technologies boosts the antitumor impact in preclinical tumor models, and induces neutralizing antibodies and T-cell responses against each viral and bacterial antigens:
Per Norlén continues, “By encoding the immune-stimulating molecule CCL19 into either DNA or mRNA vaccines, we have demonstrated substantial enhancement of the vaccines effectiveness. We think that this advancement holds immense possible for vaccine improvement, as it boosts each B cell and T cell immune responses, generating it applicable to a wide variety of vaccines. Constructing on the encouraging preclinical final results, the subsequent step is to validate the technologies in individuals.”
Evaxion aims to bring the genetic adjuvant technologies into clinical trials later this year as element of the customized cancer immunotherapy system EVX-03.
Please check out the Investors section of Evaxion’s web-site to access a replay of the R&D Day presentations.
Evaxion Biotech A/S is a pioneering enterprise building AI-powered immunotherapies. Evaxion’s proprietary and scalable AI technologies decode the human immune technique to find out and create novel immunotherapies for cancer, bacterial ailments, and viral infections. Evaxion has a broad pipeline of candidates, like 3 customized cancer immunotherapies. It is positioned in Hørsholm, Denmark, with 50 staff listed on the Nasdaq New York stock exchange. For extra data, please check out www.evaxion-biotech.com.
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