Space Biology on ISS

NASA

SPACELINE Existing Awareness Lists are distributed by means of listserv and are offered on the NASA Activity Book web site at https://taskbook.nasaprs.com/Publication/spaceline.cfm. 

Please send any correspondence to Shawna Byrd, SPACELINE Existing Awareness Senior Editor, [email protected].

Get in touch with for articles to cite in the weekly lists: Authors at NASA Centers and NASA PIs—do you have an write-up that has not too long ago published or will publish in the upcoming weeks inside a peer-reviewed journal and is in the scope of space life sciences? If so, send it our way! Send your write-up to the e-mail address talked about above. Articles received by Wednesday will seem inside that week’s list—articles received immediately after Wednesday will seem the following week.

Papers deriving from NASA assistance:

1

Faerman A, Clark JB, Sutton JP.

Neuropsychological considerations for lengthy-duration deep spaceflight.

Front Physiol. 2023 May possibly 1914:1146096. Assessment.

https://doi.org/ten.3389/fphys.2023.1146096

Note: This write-up is portion of Study Subject “Brains in Space: Effects of Spaceflight on the Human Brain and Behavior-Volume II” (https://www.frontiersin.org/investigation-subjects/47491/brains-in-space-effects-of-spaceflight-on-the-human-brain-and-behavior—volume-ii#overview). The Study Subject also involves articles from prior Existing Awareness Lists #1,041 https://doi.org/ten.3389/fphys.2023.1141078 and #1,046 https://doi.org/ten.3389/fncir.2023.1135434. This write-up could be obtained on-line with out charge.

Journal Effect Element: 3.342

Funding: “Support from the Translational Study Institute for Space Well being via NASA Cooperative Agreement NNX16AO69A is gratefully acknowledged. JS is supported by the Friedkin Chair for Study in Sensory Program Integration and Space Medicine at Baylor College of Medicine.”

two

Shelhamer M, Antonsen E, Reynolds R.

The will need for a systems strategy in spaceflight well being and medicine.

2023 IEEE Aerospace Conference. 2023 May possibly 15.

https://doi.org/ten.1109/aero55745.2023.10115773

PI: M. Shelhamer

Note: This write-up is a conference proceeding published by a peer-reviewed journal.

Journal Effect Element: 0.88

Funding: “MS is supported by NASA 80NSSC19K0487.”

three

Shelhamer M, Gersh JR.

A mission architecture to integrate human and spacecraft functional overall performance.

2023 IEEE Aerospace Conference. 2023 May possibly 15:1-eight.

https://doi.org/ten.1109/aero55745.2023.10115715

PI: M. Shelhamer

Note: This write-up is a conference proceeding published by a peer-reviewed journal.

Journal Effect Element: 0.88

Funding: “MS is supported by NASA 80NSSC19K0487.”

four

Hilditch CJ, Pradhan S, Costedoat G, Bathurst NG, Glaros Z, Gregory KB, Shattuck NL, Flynn-Evans EE.

Sex variations in perceptions of sleep inertia following nighttime awakenings.

Sleep Adv. 20234(1):zpac043.

https://pubmed.ncbi.nlm.nih.gov/37193286

Note: This write-up could be obtained on-line with out charge.

Journal Effect Element: Not offered for this journal

Funding: “This function was supported in portion by the Naval Health-related Study Center’s Naval Sophisticated Health-related Improvement System (MIPR N3239820WXHN007) and the National Aeronautics and Space Administration Airspace Operations and Security System, Program Wide Security.”

five

Saint-Guillain M, Vanderdonckt J, Burny N, Pletser V, Vaquero T, Chien S, Karl A, Marquez J, Wain C, Comein A, Casla IS, Jacobs J, Meert J, Chamart C, Drouet S, Manon J.

Enabling astronaut self-scheduling working with a robust sophisticated modeling and scheduling technique: An assessment for the duration of a Mars analogue mission.

Adv Space Res. 2023 Apr five. On the net ahead of print.

https://doi.org/ten.1016/j.asr.2023.03.045

Note: From the abstract: “Human lengthy duration exploration missions (LDEMs) raise a quantity of technological challenges. This paper addresses the query of the crew autonomy: as the distances improve, the communication delays and constraints have a tendency to avoid the astronauts from getting monitored and supported by a true time ground manage.”

Journal Effect Element: 2.611

Funding: T. Vaquero and S. Chien are affiliated with NASA Jet Propulsion Laboratory. J. Marquez is affiliated with NASA Ames Study Center.

six

Schroeck H, Whitty MA, Martinez-Camblor P, Voicu S, Burian BK, Taenzer AH.

Anaesthesia clinicians’ perception of security, workload, anxiousness, and tension in a remote hybrid suite compared with the operating area.

Br J Anaesth. 2023 May possibly 16S0007-0912(23)00203-9. On the net ahead of print.

https://pubmed.ncbi.nlm.nih.gov/37202262

Journal Effect Element: 11.719

Funding: B.K. Burian is affiliated with NASA Ames Study Center.

7

Li M, Lee JD.

Modeling aim alignment in human-AI teaming: A dynamic game theory strategy.

Proc Hum Aspects Ergon Soc Annu Meet. 2022 Oct66(1):1538-42.

https://doi.org/ten.1177/1071181322661047

PI: J.D. Lee

Note: This write-up is a meeting proceedings that published in peer-reviewed Sage journals. This write-up could be obtained on-line with out charge.

Journal Effect Element: 3.598

Funding: “This function was supported by NASA Human Study System No. 80NSSC19K0654.”

eight

Buettmann EG, Chlebek C, Lockard CA, Clayton SW, Lewis KJ, Collins KH.

Post or perish? Social media approaches for disseminating orthopedic investigation.

J Orthop Res. 2023 May possibly ten. On the net ahead of print.

https://doi.org/ten.1002/jor.25588

PI: E.G. Buettmann

Note: This write-up could be obtained on-line with out charge.

Journal Effect Element: 3.103

Funding: “Dr. Evan Buettmann was supported by the Translational Study Institute for Space Well being (TRISH) via Cooperative Agreement with NASA (NNX16AO69A). Dr. Kelsey Collins was supported by NIAMS (Grant K99AR078949).”

_______________________________________________________

Other papers of interest:

1

Almosa AS, Lockwood MB, Green SJ.

Effects of spaceflight on the human gastrointestinal tract microbiome.

J Indian Inst Sci. 2023 May possibly 23. Assessment.

https://doi.org/ten.1007/s41745-023-00384-7

Note: From the abstract: “In this quick critique, we summarize the present state of expertise on the impact of space travel on the human gut microbiome, which includes investigation styles that incorporate animals (rodents), humans, and novel simulations. Experiments had been carried out beneath situations of spaceflight, ground-primarily based, and analogous flight simulation.”

two

Ejova A, Searston RA, Stephens R, Semmler C.

Clear pondering in deep space: A guide by cognitive scientists.

In: de Zwart M, Henderson S, Culton J, Turnbull D, Srivastava A, eds. Human Makes use of of Outer Space: Return to the Moon. Singapore: Springer Nature Singapore, 2023. p. 31-47.

https://doi.org/ten.1007/978-981-19-9462-three_three

three

Oxlad M, Whitburn S, Carter AJ.

Optimizing mission results: A holistic strategy to picking the very best people today to travel to space.

In: de Zwart M, Henderson S, Culton J, Turnbull D, Srivastava A, eds. Human Makes use of of Outer Space: Return to the Moon. Singapore: Springer Nature Singapore, 2023. p. five-29.

https://doi.org/ten.1007/978-981-19-9462-three_two

four

Sakaki T, Koizumi T, Ikeido Y, Soga K, Wakabayashi K, Hoson T.

Improve in steryl glycoside levels and stimulation of lipid raft formation in azuki bean epicotyls beneath hypergravity situations.

Life Sci Space Res. 2023 Aug 2338:53-eight.

https://doi.org/ten.1016/j.lssr.2023.05.005

Note: A centrifuge was made use of in this study.

five

Lv W, Peng X, Tu Y, Shi Y, Song G, Luo Q.

YAP [Yes-associated protein] inhibition alleviates simulated microgravity-induced mesenchymal stem cell senescence by means of targeting mitochondrial dysfunction.

Antioxidants. 2023 Apr 2312(five):990.

https://doi.org/ten.3390/antiox12050990

Note: A 2D clinostat was made use of in this study. From the abstract: “Weightlessness in space leads to bone loss, muscle atrophy, and impaired immune defense in astronauts. Mesenchymal stem cells (MSCs) play important roles in keeping the homeostasis and function of the tissue. Nonetheless, how microgravity impacts the traits MSCs and the connected roles in the pathophysiological modifications in astronauts stay barely recognized.” This write-up is portion of Subject “Advances in Astrobiology” (https://www.mdpi.com/subjects/T9B7L6S956). This write-up could be obtained on-line with out charge.

six

Shamei A, Sóskuthy M, Stavness I, Gick B.

Postural adaptation to microgravity underlies fine motor impairment in astronauts’ speech.

Sci Rep. 2023 May possibly 2213:8231.

https://pubmed.ncbi.nlm.nih.gov/37217497

Note: From the write-up: “The authors declare that the information made use of inside this evaluation was obtained from publicly offered sources, and all investigation was completed in accordance with human investigation ethics recommendations and regulations. The National Aeronautics and Space Administration (NASA) gives audio and video for a choice of missions via the public NASA photos archive, which consists of audio and video files of Astronaut interviews for chosen missions. Audio files from every mission had been chosen due to the fact they function substantial speech information (amongst 70 and 120 s of speech) of astronauts promptly ahead of and immediately after their respective missions, enabling direct comparisons of vowel space ahead of and immediately after adaptations to microgravity. We evaluated vowel formants from 4 astronauts across 4 STS missions: (i) STS-129 (ii) STS-133, (iii) STS-134, and (iv) STS-135.” This write-up could be obtained on-line with out charge.

7

Yue Y, Yang J-Q, Lu S-Y, Ge J, Nie H-Y, Liu K-G, Liu F, Li H, Yan H-F, Zhang T, Sun P-M, Sun H-W, Yang J-W, Zhou J-L, Cui Y.

Simulated microgravity altered the proliferation, apoptosis, and extracellular matrix formation of L929 fibroblasts and the transforming development issue-β1/Smad3 signaling pathway.

Skin Res Technol. 2023 May possibly 829(five):e13341. On the net ahead of print.

https://doi.org/ten.1111/srt.13341

Note: A rotary cell culture technique was made use of in this study. This write-up could be obtained on-line with out charge.

eight

Zhang Y, Huang H, Yao C, Sun X, He Q, Choudharyc MI, Chen S, Liu X, Jiang N.

Fresh Gastrodia elata blume alleviates simulated weightlessness-induced cognitive impairment by regulating inflammatory and apoptosis-connected pathways.

Front Pharmacol. 2023 May possibly 314:1173920.

https://pubmed.ncbi.nlm.nih.gov/37205911

Note: Hindlimb unloading study. This write-up is portion of Study Subject “Exploring the Essential Targets and Compounds That Manipulate Brain Neurocircuits Against Mental Issues and Psychiatric” (https://www.frontiersin.org/investigation-subjects/44928/exploring-the-crucial-targets-and-compounds-that-manipulate-brain-neurocircuits-against-mental-problems-and-psychiatric#overview). The Study Subject also involves an write-up from prior Existing Awareness List #1,050 https://doi.org/ten.3389/fphar.2023.1167398. Extra articles will be forthcoming and could be discovered in the hyperlink to the Study Subject. This write-up could be obtained on-line with out charge.

9

Sim HJ, So HS, Poudel SB, Bhattarai G, Cho ES, Lee JC, Kook SH.

Osteoblastic Wls ablation protects mice from total physique irradiation-induced impairments in hematopoiesis and bone marrow microenvironment.

Aging Dis. 2023 Jun 114(three):919-36.

https://pubmed.ncbi.nlm.nih.gov/37191410

Note: This write-up could be obtained on-line with out charge.

ten

Zhang Q, Gerweck LE, Cascio E, Gu L, Yang Q, Dong X, Huang P, Bertolet A, Nesteruk KP, Sung W, McNamara AL, Schuemann J.

Absence of tissue-sparing effects in partial proton FLASH irradiation in murine intestine.

Cancers (Basel). 2023 Apr 1315(eight):2269.

https://pubmed.ncbi.nlm.nih.gov/37190197

Note: This write-up could be obtained on-line with out charge.

11

Waldbaum JDH, Xhumari J, Akinsuyi OS, Arjmandi B, Anton S, Roesch LFW.

Association amongst dysbiosis in the gut microbiota of principal osteoporosis individuals and bone loss.

Aging Dis. 2023 Apr 28. Assessment.

https://pubmed.ncbi.nlm.nih.gov/37199579

Note: This write-up could be obtained on-line with out charge.

12

Badakva AM, Miller NV, Zobova LN.

Integration of vestibular, visual, and proprioceptive inputs in the cerebral cortex for the duration of movement manage.

Hum Physiol. 2023 Apr 2749(two):176-82. Assessment.

https://doi.org/ten.1134/S0362119722600515

13

Kelly KR, Palombo LJ, Jensen AE, Bernards JR.

Efficacy of closed cell wet-suit at a variety of depths and gas mixtures for thermoprotection for the duration of military education dives.

Front Physiol. 2023 May possibly 2414:1165196.

https://doi.org/ten.3389/fphys.2023.1165196

Note: This write-up could be obtained on-line with out charge.